Sonographic Measurements of Intrahepatic Inferior Vena Cava, Liver Span, and Common Bile Duct: Normative Data and Respiratory Variability in Adult Nigerian Population

Main Article Content

Mohammed Lawan Mohammed
Dr. Maryam Abba Goni
Dr. Mohammed Lawan Mohammed
Dr. Ibrahim Abba Tijjani
Dr. Umar Hassan Umar
Dr. Abubakar Farate
Dr. Zara Mohammed Bata
Dr. Zara Baba Shettima
Dr. Ruqayyatu Abubakar Imam

Abstract

ABSTRACT


Background: Population-specific reference values for sonographic measurements are essential for accurate clinical interpretation. While ultrasound is widely used in Nigeria, comprehensive normative data for intra-abdominal vascular structures, particularly the inferior vena cava (IVC), are limited for the Nigerian population.


Objective: To establish normative reference values for intrahepatic IVC diameter, liver span, and common bile duct (CBD) diameter in healthy adults in North-Eastern Nigeria, and to evaluate their variations with respiration, age, and gender.


Methods: A prospective study of 150 healthy adults comprising 78 males and 72 females, aged 19-70 years. B-mode ultrasound using a GE Logic S8 with 3-5MHz transducer was use to measure intrahepatic IVC diameter (transverse and longitudinal) during inspiration and expiration, liver span in mid-clavicular line, and CBD diameter. Collapsibility index was calculated. Statistical analysis included descriptive statistics, Student's t-test, and Pearson's correlation.


Results: Mean age was 41.72±13.20 years. Normative values were: IVC transverse diameter (inspiration: 1.48±0.51 cm; expiration: 1.80±0.50 cm), IVC longitudinal diameter (inspiration: 1.43±0.53 cm; expiration: 1.71±0.51 cm), average IVC diameter (inspiration: 2.19±0.52 cm; expiration: 2.66±0.50 cm), IVC collapsibility index (21.4±8.7%), liver span (13.4±1.8 cm), and CBD diameter (inspiration: 0.22±0.04 cm; expiration: 0.30±0.07 cm). No significant gender differences were found in IVC dimensions (p>0.05). Weak positive correlation was found between age and liver span (r=0.177, p=0.030).


Conclusion: This study establishes comprehensive normative sonographic values for intrahepatic IVC, liver span, and CBD in a Nigerian population. The IVC collapsibility index of 21.4% provides a reference for assessing intravascular volume status. These population-specific values will enhance the accuracy of ultrasound interpretation in clinical practice in Nigeria and similar populations.

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Sonographic Measurements of Intrahepatic Inferior Vena Cava, Liver Span, and Common Bile Duct: Normative Data and Respiratory Variability in Adult Nigerian Population (M. L. Mohammed, M. Abba Goni, M. Lawan Mohammed, I. Abba Tijjani, U. Hassan Umar, A. Farate, Z. Mohammed Bata, Z. Baba Shettima, & R. Abubakar Imam, Trans.). (2026). West African Journal of Allied Health Sciences, 2(2). https://doi.org/10.67891/9jj9yt70

References

1. Kocher HM, Berry DP. Ultrasound measurements: the need for standardisation. Br J Radiol. 2007; 80(955): 537-540.

2. World Health Organization. WHO Manual of Diagnostic Ultrasound. 2nd ed. Geneva: WHO Press; 2011.

3. International Federation of Clinical Chemistry. Establishment and use of reference values. Scand J Clin Lab Invest. 1987; 47(Suppl 186): 5-11.

4. Kircher BJ, Himelman RB, Schiller NB. Noninvasive estimation of right atrial pressure from the inspiratory collapse of the inferior vena cava. Am J Cardiol. 1990; 66(4): 493-496.

5. Ciozda W, Kedan I, Kehl DW, et al., The efficacy of sonographic measurement of inferior vena cava diameter as an estimate of central venous pressure. Cardiovasc Ultrasound. 2016; 14: 33.

6. Barbier C, Loubières Y, Schmit C, et al., Respiratory changes in inferior vena cava diameter are helpful in predicting fluid responsiveness in ventilated septic patients. Intensive Care Med. 2004; 30(9): 1740-1746.

7. Premkumar M, Rangegowda D, Kajol K, et al., Noninvasive estimation of intravascular volume status in cirrhosis by dynamic size and collapsibility indices of the inferior vena cava using bedside echocardiography. J Gastroenterol Hepatol. 2019; 34(2): 322-328.

8. Kitamura H, Kobayashi C. Impairment of change in diameter of hepatic portion of the IVC. J Ultrasound Med. 2005; 24: 355-359.

9. Nzeh DA, Adedoyin MA. Sonographic assessment of the normal common bile duct diameter in Nigerians. Afr J Med Med Sci. 1989; 18(4): 305-307.

10. Danbatta AH. B-mode ultrasonic measurement of inferior vena cava diameter among healthy adults in Kano, Nigeria. Niger J Basic Clin Sci. 2016; 13(2): 94-98.

11. Masugata H, Senda S, Okuyama H, et al., Age-related decrease in inferior vena cava diameter measured with echocardiography. Tohoku J Exp Med. 2010; 222(2): 141-147.

12. American Institute of Ultrasound in Medicine. AIUM practice guideline for the performance of an ultrasound examination of the abdomen and/or retroperitoneum. J Ultrasound Med. 2012; 31(8): 1301-1312.

13. Solberg HE. Establishment and use of reference values. In: Burtis CA, Ashwood ER, Bruns DE, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 5th ed. St. Louis: Elsevier Saunders; 2012: 425-448.

14. Chuo LS, Mahmud R, Salih QA. Colour Doppler ultrasound examination of the main portal vein and inferior vena cava in normal Malaysian adult population. Internet J Cardiovasc Res. 2004; 2(2): 1-6.

15. Gnanasaekaran N, Neelakandan A, Subbaraman S, et al., Measurement of inferior vena cava parameters in the normal adult Indian population using transabdominal ultrasound. J Evid Based Med Health. 2016; 3(55): 2795-2803.

16. Arif Khammas AS, Mahmud RS. Ultrasound measurement of the liver, gall bladder thickness, portal vein and pancreas in an urban region, Malaysia. J Med Ultrasound. 2021; 29: 26-31.

17. Lynn KS, Chen SC, Huang MH, et al., Sonographic liver size in chronic hepatitis B. Ultrasound Med Biol. 2004; 30(11): 1423-1428.

18. Salam AJ, Iyua KO, Egbo BO, et al., Hepatic Sonographic Findings at Jos University Teaching Hospital, Nigeria. Highland Med Res J. 2020; 20(2): 46-50.

19. Ojewola RW, Tijani KH, Jeje EA, et al., Sonographic determination of normal liver size in an adult Nigerian population. Niger Postgrad Med J. 2013; 20(4): 305-309.

20. Adeyekun AA, Ifijeh OA, Akhigbe AO, et al., Ultrasound reference values for inferior vena cava diameter and collapsibility index among adult Nigerians. West Afr J Radiol. 2019; 26: 25-30.

21. International Society of Ultrasound in Obstetrics and Gynecology. Sonographic examination guidelines. Ultrasound Obstet Gynecol. 2011; 38(1): 108-113.

22. Koo TK, Li MY. A guideline of selecting and reporting intraclass correlation coefficients for reliability research. J Chiropr Med. 2016; 15(2): 155-163.

23. Streiner DL. Maintaining standards: differences between the standard deviation and standard error, and when to use each. Can J Psychiatry. 1996; 41(8): 498-502.

24. Chen T, Hung CR, Huang AC, et al., The diameter of the common bile duct in an asymptomatic Taiwanese population: measurement by magnetic resonance cholangiography. J Chin Med Assoc. 2012; 75(8): 384-388.

25. Friedrich-Rust M, Ong MF, Martens S, et al., Performance of transient elastography for the staging of liver fibrosis: a meta-analysis. Gastroenterology. 2008; 134(4): 960-974.